Rabbit Secondary Antibodies
ABclonal Technology PE Rabbit anti-Mouse CD56/NCAM
Predicted to enable LRR domain binding activity and phosphatase binding activity Involved in commissural neuron axon guidance and regulation of semaphorin-plexin signaling pathway Acts upstream of or within several processes including homotypic cell-cell adhesion positive regulation of calcium-mediated signaling and regulation of exocyst assembly Located in several cellular components including external side of plasma membrane growth cone and neuronal cell body Is expressed in several structures including embryo mesenchyme nervous system sensory organ skin and urinary system Human ortholog(s) of this gene implicated in bipolar disorder middle cerebral artery infarction and pancreatic cancer Orthologous to human NCAM1 (neural cell adhesion molecule 1)
Jackson Immuno Research Labs Peroxidase-AffiniPure Rabbit Anti-Mouse IgG F(ab')2 Fragment Specific
Peroxidase-AffiniPure Rabbit Anti-Mouse IgG F(ab')2 Fragment Specific
Jackson Immuno Research Labs Peroxidase-AffiniPure Rabbit Anti-Mouse IgG + IgM (H+L)
Peroxidase-AffiniPure Rabbit Anti-Mouse IgG + IgM (H+L)
ABclonal Technology PE Rabbit anti-Mouse CD8a mAb
Enables identical protein binding activity Acts upstream of or within several processes including cytotoxic T cell differentiation defense response to virus and positive regulation of calcium-mediated signaling Located in external side of plasma membrane Is expressed in several structures including endocrine gland exocrine gland genitourinary system gut and hemolymphoid system gland Orthologous to human CD8A (CD8a molecule)
ABclonal Technology PE Rabbit anti-Mouse IgG1 mAb
Mouse IgG1 is a subtype of immunoglobulin G antibody that is produced by B cells in response to an antigen It is the most abundant IgG subtype in the serum and plays a crucial role in the adaptive immune response Mouse IgG1 is composed of two heavy chains and two light chains and it is involved in opsonization complement activation and antibody-dependent cell-mediated cytotoxicity It is also involved in the regulation of immune responses including the activation of T cells and the inhibition of B cell activation Mouse IgG1 is widely used in research and diagnostic applications including ELISA Western blotting and immunohistochemistry It is also used in therapeutic applications such as immunotherapy and vaccine development
ABclonal Technology APC Rabbit anti-Mouse CD11b
Enables complement component C3b binding activity heparan sulfate proteoglycan binding activity and heparin binding activity Contributes to cargo receptor activity Involved in several processes including central nervous system development endocytosis and positive regulation of neuron death Acts upstream of or within several processes including activated T cell proliferation leukocyte migration and microglia development Located in external side of plasma membrane and nucleus Is integral component of membrane Part of integrin alphaM-beta2 complex Is expressed in several structures including central nervous system heart lymphatic vessel thymus and yolk sac Human ortholog(s) of this gene implicated in lupus nephritis Orthologous to human ITGAM (integrin subunit alpha M)
ABclonal Technology PE Rabbit anti-Mouse Ly-49D
Predicted to enable carbohydrate binding activity Predicted to act upstream of or within cell adhesion Located in external side of plasma membrane
ABclonal Technology PE Rabbit anti-Mouse/Rat CD54
This gene encodes an integral membrane protein that binds leukocyte adhesion protein LFA-1 It participates in the innate immune response
ABclonal Technology PE Rabbit anti-Mouse TNF-a mAb
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily Members of this family are classified based on primary sequence function and structure This protein is synthesized as a type-II transmembrane protein and is reported to be cleaved into products that exert distinct biological functions It plays an important role in the innate immune response as well as regulating homeostasis but is also implicated in diseases of chronic inflammation In mouse deficiency of this gene is associated with defects in response to bacterial infection with defects in forming organized follicular dendritic cell networks and germinal centers and with a lack of primary B cell follicles Alternative splicing results in multiple transcript variants
ABclonal Technology PerCP Rabbit anti-Mouse CD4
Predicted to enable several functions including interleukin-16 binding activity interleukin-16 receptor activity and protein homodimerization activity Involved in helper T cell enhancement of adaptive immune response Acts upstream of or within several processes including defense response to Gram-negative bacterium positive regulation of calcium-mediated signaling and positive regulation of peptidyl-tyrosine phosphorylation Located in endoplasmic reticulum external side of plasma membrane and membrane raft Is expressed in several structures including alimentary system brain genitourinary system hemolymphoid system and liver and biliary system Used to study type 1 diabetes mellitus Human ortholog(s) of this gene implicated in immunodeficiency 79 Orthologous to human CD4 (CD4 molecule)
ABclonal Technology PE Rabbit anti-Mouse CD32 mAb
CD32 (Fcgr2) is a 40 kD transmembrane glycoprotein member of the immunoglobulin superfamily The extracellular region of CD32 consists of two Ig C-type domains that binds the Fc region from monomeric IgG with low affinity but binds immune complexes efficiently CD32 can mediate phagocytosis of immune complexes and modulate cell activation CD32 is expressed by Macrophages neutrophils mast cells and B cells